CSKA Moscow - Real Madrid
Real Madrid topped Group D with 18 points and a +17 goal difference, the best Champions League Group Stage performance in history.
Real Madrid have qualified to the Champions League knockout stage for the 15th consecutive season, currently the longest run.
CSKA have lost three of their last four European matches on home soil.
The Russian club have never lost a European match against Spanish opposition, winning three and drawing two.
Real Madrid have lost just one of their last 19 Champions League games and won all six so far this season.
Madrid have kept five clean sheets in their six Champions League matches this season (more than any other team) and in all three away games.
Real Madrid have kept 13 clean sheets in 18 Champions League games under Jose Mourinho.
After winning none of their first seven European games away in Russia, Real Madrid have won the last two trips.
Jose Mourinho has lost just three of his last 31 matches as a coach in the Champions League, with all three defeats at the hands of Barcelona.
Real Madrid's José Callejón has scored a brace in each of his two Champions League starts; the former Espanyol player has converted 83% of his shots this term in Europe.
56% of CSKA Moscow's Champions League goals this season have been scored by Seydou Doumbia (five out of nine).
Iker Casillas was the only goalkeeper with a 100% save percentage in this season's Champions League Group Stage, keeping a clean sheet in all of his five appearances.
Napoli - Chelsea
Chelsea's only win in 10 European away matches on Italian soil came against Lazio in November 2003 (4-0).
The Blues have won just three of their six Champions League matches this season despite having taken the lead in all six games.
Chelsea fired in the most shots on target in the 2011/12 Champions League Group Stage (54).
Napoli had the best conversion rate in the Group Stage, scoring with 22% of their shots.
All four of the goals Chelsea have conceded this season in the Champions League have come in the second half.
Five of the six goals Napoli have shipped this term in the Champions League have been conceded in the first half.
No English club have ever won at Napoli in European competition (two draws and two defeats).
The Blues have drawn Italian opposition in two of the last three seasons at this stage, beating Juventus in 2008/09 and losing to Inter in 2009/10.
Chelsea haven't won back to back Champions League games since November 2010.
The Londoners have won just one of their last six Champions League away games and none of the last four.
Didier Drogba has scored four goals in his last three Champions League appearances.
No goalkeeper has managed to save a shot on target from Napoli striker Edinson Cavani this season in the Champions League (four goals in as many shots on target).
Marseille -Internazionale
Inter and Marseille met in the 2003/04 UEFA Cup quarter-final, with the French team winning both legs 1-0.
Marseille have never scored more than once in their 14 encounters against Italian opposition in Europe (excluding Intertoto Cup).
Marseille are the only team to have won a Champions League game this season after going two goals down (following their crucial 3-2 win over Borussia Dortmund).
Inter have won four and lost six of their last 11 Champions League matches.
Marseille's record against Italian sides is even, with five wins, five defeats and four draws in 14 games.
Inter's last four Champions League goals have been scored by four different Argentine players (Samuel, Milito, Álvarez and Cambiasso).
After four clean sheets in a row on home soil in the Champions League, Marseille have suffered two consecutive 1-0 defeats at Stade Vélodrome.
Marseille posted the worst shooting accuracy of the teams who qualified for the Last 16, hitting the target with just 38% of their attempts.
Internazionale scored more goals from corners than any other side this season in the Champions League Group Stage (three).
Basel - Bayern Munich
Basel conceded more goals than any other the other teams who qualified for the Last 16 (10).
Basel are the first Swiss side to reach the knock out stage in the Champions League era.
The Swiss side are the only team in the Last 16 yet to keep a clean sheet in this season's competition.
Franck Ribery was fouled more often than any other player in the Champions League Group Stage (23).
Nine of the 11 goals Bayern have scored have been netted in the first half, the highest proportion of any team in the Group Stage this season (82%).
Basel have scored three goals on counter attacks this season, more than any other side in the Champions League Group Stage.
Bayern have played five matches against Swiss sides in Europe, winning four, including a win home and away against Basel in the 20010-11 Champions League Group Stage.
FC Basel have won none and lost four of their six European games against German opposition.
Basel have lost just one of their last seven matches in Europe.
Alexander Frei has netted eight goals in just 11 Champions League appearances (excluding qualifiers).