Despite currently sitting eight points above the relegation zone, Owen Coyle will be desperate for his side to recapture their best form, with Bolton failing to win in any of their last five league games.
For Wolves, the consequences are much more significant and should they fail to better West Ham’s result against Blackpool, then they will replace the Hammers at the bottom of the table.
However, there will be no lack of motivation from Mick McCarthy's men, with the Midlands side able to move out of the drop zone if results go their way.
The task is likely to be a difficult one, however, with Wolves suffering defeats in both fixtures against Bolton last season, although they have shown their ability to upset the odds with victories over both Chelsea and Liverpool and scoring three goals away to Manchester City in recent league fixtures.
TEAM NEWS
Bolton Wanderers
Daniel Sturridge goes straight into the Bolton Wanderers squad after completing his loan move from Chelsea until the end of the season.
Sturridge could be named in the starting line-up and would likely replace Johan Elmander alongside Kevin Davies.
David Wheater is expected to make his first league appearance for Bolton after joining from Middlesbrough.
The 28-year-old featured for the Trotters in their 0-0 FA Cup fourth round tie against Wigan Athletic at the weekend and should remain in the starting line-up.
Gary Cahill and Stuart Holden were rested for the visit of Wigan and will be recalled for the Premier League clash.
Ivan Klasnic, who has recovered from a groin injury, was an unused substitute in the FA Cup tie and could hand Owen Coyle an option in attack, while Lee Chung-Yong is back in the country after representing South Korea in the Asian Cup in Qatar, where they beat Uzbekistan in the third place play-off.
The midfielder is likely to be rested after his exploits for his country but may feature as a substitute.
Jlloyd Samuel, Ricardo Gardner, Sean Davis and Joey O'Brien all remain absent through respective injuries and are some time away from a return.
Possible starting XI: Jaaskelainen; Ricketts, Cahill, Wheater, Robinson; M Davies, Muamba, Holden, Taylor; Sturridge, K Davies.
Wolves
Wolves have made two late acquisitions during the January transfer window with the signing of Brazilian goalkeeper Adriano Basso and the loan capture of Tottenham midfielder Jamie O’Hara.
O’Hara has been injured for most of the season but is believed to have recovered from a back injury to put him in contention to feature at Bolton, although most likely as a substitute.
Basso, however, has been brought in as emergency cover and is unlikely to even make the bench.
Sylvan Ebanks-Blake has recovered from a calf strain and could return after appearing as a late substitute in Wolves’ 1-0 defeat to Stoke City in the FA Cup, while Sam Vokes was also a late substitute and could be included in the squad.
Dave Edwards missed Wolves' fourth round FA Cup exit after suffering an illness and is unlikely to be named in the squad, and Wayne Hennessey will replace Marcus Hahnemann in goal after the American stepped in against Stoke.
Michael Kightly remains sidelined after undergoing knee surgery and is still several weeks away from full training, while Adlene Guedioura is another long term absentee with a broken leg.
Possible starting XI: Hennessey; Zubar, Stearman, Berra, Ward; Jarvis, Foley, Milijas, Fletcher; Ebanks-Blake, Doyle.
Prediction
Bolton have been very poor of late but the signing of Daniel Sturridge may just be enough to galvanise the squad, and the home crowd will give them the edge.
Editor's Prediction
Bolton 2-1 Wolves 
